Research
Extramural Grants received during last 5 Years as on 1st January 2015:

Dept. of Pathology

Name of faculty Research project Grant giving agency Year of sanction with duration Amount sanctioned
(in lakhs)
Prof. Madhumita Mukhopadhyay Role of Calretinin Staining in Hirschsprung’s Disease in  Infants DST (West Bengal) 2013-16 12,43,000
Prof. Chhanda Dutta IDH expression in gliomas DBT (West Bengal) 2015-18 28,00,000

Dept. of Biochemistry


Name of faculty Research project Grant giving agency Year of sanction with duration Amount sanctioned
(in lakhs)
Prof. Sasanka Chakrabarti Role of a-synuclein and parkin in dopamine toxicity on SHSY5Y cells: implications for sporadic Parkinson's Disease. DST, Govt. of India 2013-16 39,56,000/-
Prof. Sasanka Chakrabarti Identification of Molecular Links between amyloid precursor protein (APP) metabolism and disease related biomarkers in an experimental model with SHSY5Y cells DBT, Govt. of India 2013-16 67,01700/-
Prof. Sasanka Chakrabarti Elucidation of the mechanisms of dopamine induced mitochondrial damage and search for neuroprotective agents: an experimental study with rat brain mitochondria and PC-12cells with implications in Parkinson's disease. BRNS 2009-12 17,00, 000/-
Prof. Sasanka Chakrabarti Elucidation of different mechanisms of mitochondrial dysfunction in adipose tissue of type 2 diabetes patients with or without obesity. CSIR, Govt. of India 2009-12 20,00000/-
Prof. Sasanka Chakrabarti Elucidation of different mechanisms of amyloid β protein (Aβ) toxicity in young and aged rat brain: an experimental study with brain subcellular fractions and animal models with implications in Alzheimer’s disease. DST, Govt. of India 2009-12 27,25,000

Dept. of Rheumatology & Clinical Immunology

Name of faculty Research project Grant giving agency Year of sanction with duration Amount sanctioned
(in lakhs)
Prof. Alakendu Ghosh. Epidemiological evaluation of “Low Back Pain” prevalent among different strata of people in West Bengal. W. Bengal State Health & Family Welfare Samiti   10,59,700
Prof. Alakendu Ghosh To determine the prevalence and cut-off of anti-cyclic citrullinated peptide (anti-CCP) antibody in our population DST (West Bengal)
2008-11
 
2008-11 8,64,400
Prof. Alakendu Ghosh To determine the prevalence of hyperlipidemia, atherosclerosis and endothelial dysfunction in patients with early rheumatoid arthritis, and their response to therapy with disease modifying anti-rheumatic drugs (DMARDs) ICMR, Govt. of india 2009-12   15,52,750
Prof. Alakendu Ghosh / Dr. PS Mahapatra Evaluation of Immunomodulatory activity of Black Tea extract in Rheumatoid arthritis: an in vitro study of expresiion of inflammatory molecules and cytokines in synovial fluid and tissue cells of patients with Rheumatoid arthritis Tea Board   2012-15 15,20,000

Dept. of Pharmacology


Name of faculty Research project Grant giving agency Year of sanction with duration Amount sanctioned
(in lakhs)
Prof. Mitali Chatterjee ‘Evaluation of molecular markers for monitoring of Post Kala-azar Dermal Leishmaniasis (PKDL) in West Bengal’ ICMR, Govt. of India 2012-15 38.85
Prof. Mitali Chatterjee Role of IL 10 and T-regulatory cells in the Immunopathogenesis of Indian Post Kala–Azar Dermal Leishmaniasis (PKDL) CSIR, Govt. of India 2010-13 25.76
Prof. Mitali Chatterjee Therapeutic effectiveness of allylpyrocatechol (APC) in an experimental model of Arthritis DBT, Govt. of India 2012-15 49.25
Prof. Mitali Chatterjee Targeting thiol mediated anti-oxidant pathways as a potential chemotherapeutic modalities in Indian Leishmaniasis DST, Govt. of India 2010-13 20.00
Prof. Mitali Chatterjee Study of Immunological determinants at the lesional site of patients with PKDL (Indo-German collaborative grant) ICMR, Govt. of India 2010-12 5.00
Prof. Mitali Chatterjee Effectiveness of Artemisinin and its analogues as potential anti-leishmanial agents ICMR, Govt. of India 2009-12 16.36
Prof. Mitali Chatterjee Visceral leishmaniasis; identification and validation of biomarkers for antimony susceptibility / resistance in clinical isolates of leishmania donovani DBT, Govt. of India 2009-12 18.24
Prof. Mitali Chatterjee Evaluation of immunomodulatory activity of leaves of Piper betle linn. (paan) in patients with Prof. Mitali Chatterjee Rheumatoid arthritis State DST (West Bengal) 2008-11 12.23
Prof. Mitali Chatterjee Evaluation of molecular mechanisms responsible for the anti-inflammatory activity of allylpyrocatechol BRNS, DAE, Govt. of India 2009-12 17.35
Prof. Mitali Chatterjee Evaluation of plant derived compounds with immunomodulatory activity in Leishmaniasis (Indo-Brazil collaborative grant) DST, Govt. of India 2009-11 10.8
Prof. Mitali Chatterjee Funds for Infrastructure (FIST programme) DST, Govt. of India Coordinator 2005-10 60.0
Prof. Mitali Chatterjee Funds for Infrastructure (FIST programme) DST, Govt. of India, Coordinator 2010-15 83.0
Prof. Suparna Chatterjee MDR1      polymorphism (C3435T) with antitubercular drug induced hepatotoxicity in eastern Indian population RD Birla Smarak Kosh 2011-13 3.0
Prof. Suparna Chatterjee Antibiotic stewardship program and advocacy of rational antimicrobial use ICMR,
Govt. of India
2014-16 Co-Investigator
Prof. Suparna Chatterjee Preclinical Toxicological studies of Black Tea with special emphasis on iron induced toxicity Tea Board of India 2011-13 3.0
Prof. Suparna Chatterjee Effect of Probiotics on carriage of Extended Spectrum Beta Lactamase producing Enterobacteriacae in neonatal gut: A Randomized controlled trial at a Tertiary care Neonatal Intensive Care Unit DBT, Govt. of India 2012-14 Co-Investigator
Dr. Avijit Hazra Preclinical and safety studies of some proprietary herbal formulations. M/s Isha Natural & Herbal Products, Hyderabad 2011-13 4.0
Dr. Avijit Hazra Department of Science & Technology (DST), Government of West Bengal Studies of some marine flora of the Sunderbans 2012-14  2.88
Dr. Amrita Sil
&
Prof. Mitali Chatterjee
Molecular epidemiological study for evaluating role of potential host factors as markers of susceptibility of leprosy in West Bengal, India German Lepra Research Assoc. GLRA, India 2015 - 17 Co-Investigators

Dept. of Endocrinology


Name of faculty Research project Grant giving agency Duration Amount sanctioned
(in lakhs)
Prof Subhankar Chowdhury
Head of Dept.
Funds for Infrastructure
(Departmental Grant)
DST, Govt. of India 2014-19 100
Prof Subhankar Chowdhury Study of the association of adiponectin gene polymorphism and level of adiponectin with inflammation and endothelial dysfunction in type 2 diabetes subjects RSSDI,
Central Body
2 years 5.0
Prof Subhankar Chowdhury Neck circumference as a predictor of impaired glucose metabolism, body mass index, cardiovascular risk factors and metabolic syndrome in normal, pre-diabetic and diabetic population: a population based observational study DST West Bengal 3 years 7.43
Prof Subhankar Chowdhury Association of gene mutations/ polymorphisms with therapeutic efficacy of metformin in type 2 diabetes mellitus patients of West bengal, India DBT, Govt. of India 3 years 10.20
Prof Subhankar Chowdhury Role of gut microbiome in gestational diabetes mellitus DBT (W. Bengal) 3years 29.93
Prof Satinath Mukhopadhyay Molecular Mechanisms of Beta Cell Apoptosis in animal models of Diabetes. DST, Govt. of India?? 3 years 35.0
Prof Satinath Mukhopadhyay Free fatty acid induced differential regulation of CPT1 and CPT2 and its contribution to insulin resistance in skeletal muscle.  CSIR, Govt. of India 3 years Co-Investigator
Prof Satinath Mukhopadhyay Insulin resistance leads to neuronal degeneration through oxidative stress in a neural cell line. DBT, Govt. of India 3 years 67.0
Prof Satinath Mukhopadhyay Role of free fatty acids in regulation of Fetuin A and NFkB gene expression in palmitate treated adipocyte cell lines. DBT, Govt. of India 3 years  
Prof Satinath Mukhopadhyay Role of TypeI interferons in insulin resistance. CSIR, Govt. of India 3 years  
Prof Satinath Mukhopadhyay Identification of genetic markers for Indian Type2 diabetics. DBT, Govt. of India 3 years 35.0
Prof Satinath Mukhopadhyay Incretin axis and DPP-IV system in Indian Type2 diabetics RSSDI (WB) 2 years 2.0
Prof Satinath Mukhopadhyay Molecular mechanisms underlying proliferative and invasive behavior of malignant ovarian tumors CSIR, Govt. of India 3 years  
Prof Satinath Mukhopadhyay Effect of DPP4 inhibition on serum erythropoietin level in diabetic nephropathy RSSDI (WB) 2 years 1.0
Prof Satinath Mukhopadhyay Study of dipeptidyl peptidase-4 in Indian type 2 diabetes RSSDI (WB) 2 years 1.0
Prof Subhankar Chowdhury A study of the demographic and clinical profile, the genetics, incretin levels, insulin resistance and correlation of exocrine and endocrine dysfunction in patients with fibrocalcific pancreatic diabetes attending S.S.K.M Hospital, Kolkata RSSDI (WB) 2 years 1.0
Prof Subhankar Chowdhury A hospital-based study on the pattern of metabolic bone disorders in diabetic patients with chronic kidney disease with special reference to detection of adynamic bone disease in diabetic kidney disease by non-invasive assessment RSSDI (WB) 2 years 1 .0
Prof Satinath Mukhopadhyay Endocrine changes in adult patients of E-Beta thalassemia with special reference to glucose homeostasis RSSDI (WB) 2 years 1.0
Prof Subhankar Chowdhury Comparison of anthropometric parameters with special reference to wrist circumference & cardio-metabolic risk factors among treatment-naïve diabetic and non-diabetic subjects attending OPD of a tertiary care hospital in Kolkata RSSDI (WB) 2 years 1.0
Prof Satinath Mukhopadhyay Role of infrared dermal thermometry in the assessment and management of diabetic foot-a prospective observational study RSSDI (WB) 2 years 0.2
Prof Subhankar Chowdhury Evaluation of hypogonadism and its relationship with type 2 Diabetes        RSSDI (WB) 2 years 0.5
Prof Satinath Mukhopadhyay Role of selenium in type 2 diabetes RSSDI (WB) 2 years 0.5
Prof Subhankar Chowdhury Role of power Doppler in evaluation & prediction of microvascular complications of diabetes RSSDI (WB) 2 years 1.86
Prof Satinath Mukhopadhyay Comparison of TCC and PRAFO in diabetic foot ulcers RSSDI (WB) 2 years 2.00
Prof Satinath Mukhopadhyay Role of Vitamin D in Pioglitazone induced bone disease in type 2 diabetes RSSDI (WB) 2 years 2.00
Prof Subhankar Chowdhury Evaluation of neck circumference as a risk factor of coronary disease in type 2 diabetes RSSDI (WB) 2 years 1.5
Prof Satinath Mukhopadhyay Prevalence of Vitamin-D deficiency and its relation to systemic inflammatory markers and insulin resistance in prediabetic subjects RSSDI (WB) 2 years 2,00,000
Prof Satinath Mukhopadhyay Prevalence of Latent Autoimmune Diabetes of Adults (LADA) among young non obese diabetics in a Tertiary Care Diabetic Centre. RSSDI (WB) 2 years 2.0
Prof Subhankar Chowdhury Impact of hypothyroidism and thyrotoxicosis on Glycated Hemoglobin in Non – diabetic subjects. RSSDI (WB) 2 years 2.0

School of Digestive & Liver diseases


Role of mitochondrial membrane potential( m) & mitochondrial permeability transition (MPT)in the initiation of Isoniazed (INH) induced liver cell injury: an in vitro study   Dr. Amal K Santra   ICMR, Govt. of India Fellowship Programme 2009 - 2011
Evaluation of the role of CYP2e1 in the mediation of liver cell injury and alteration of hepatic stellate cell behaviour in anti- tubercular drugs induced hepatotoxicity   Dr. Amal K Santra   ICMR, Govt. of India 29,29,929/- 2010 - 2013 
Differential expression of NADPH oxidase in activation, senescence and apoptosis of hepatic stellate cells during hepatic fibrosis in mice  Dr. Amal K Santra   ICMR, Govt. of India  39,94,024/- 2012 - 2015 
A multicentric randomized controlled clinical trial of lamivudine, lamivudine and adefovir, glycyrrhizin and adefovir in HBV related decompensated cirrhosis   Dr. Abhijit Chowdhury   ICMR,
Govt. of India
24,65,960/- 2007 - 2012 
Study of Hepatitis b virus (HBV) resistance patterns in patients with chronic infection during therapy with nucleoside and nucleotide analogues Dr. Abhijit Chowdhury   ICMR, Govt. of India 36,00,000/- 2009 - 2011 
Hepatic stellate cells (hscs) activation during Isoniazid induced hepatocytes injury: an in-vitro study   Dr. Abhijit Chowdhury   ICMR, Govt. of India 31,73,983/- 2011 - 2014 
Cellular events in Hepatic stellate cell activation byIsoniazid  induced necrotic hepatocytes: An In-vitro study Dr. Abhijit Chowdhury   ICMR, Govt. of India 37,17,642/-  
Functional characterization of a new putative tumour suppressor gene, hELG1/ATAD5 and its correlation with hepatitis B virus (HBV) infection. Dr. Soma Banerjee CSIR
Govt. of India
22,94,065/- 2011 – 2014
Determination of genetic susceptibility of Alcoholic Liver Disease by studying polymorphisms of selected candidate genes in North-East Indian population. Dr. Soma Banerjee DBT
Govt. of India
31,15,000/- 2012 - 2015
Identification of Hepatitis B virus DNA integration site in liver tissue of HBV related Cirrhosis and Hepatocellular carcinoma patients to understand the mechanism of Hepatocarcinogenesis. Dr. Soma Banerjee West Bengal State DST 7,51,800/- for 1st year 2013 - 2016
Identification of signature genes for development of hepatocellular carcinoma (HCC) from liver cirrhosis (LC) for patient oriented therapy. Dr. Soma Banerjee CSIR
Govt. of India
25,39,395/- 2008 - 2011
Early molecular and genetic determinants of HBV mediated progression of fibrosis to hepatocellular carcinoma. Dr. Soma Banerjee ICMR
Govt. of India
36,09,494/- 2010 - 2013
Micro RNA mediated regulation of Liver fibrosis. Dr. Soma Banerjee ICMR
Govt. of India
33,94,454/- 2010 -2013
Biology of Hepatitis B Virus of genotype D in an integrated clinico-Virological perspective. Dr. Abhijit Chowdhury DBT
Govt. of India
18,89,800/- for 1st year 2013 - 2016
Insight into the distribution and pathogenic potential of diverse Hepatitis B Virus subgenotypes underlying different clinical outcomes of chronic infection. Dr. Simanti Datta CSIR
Govt. of India
16,84,878/- for 1st & 2nd year 2012 - 2015
Tracing the dynamics of host-virus interaction in different phases of e-antigen negative chronic hepatitis B infection. Dr. Simanti Datta ICMR
Govt. of India
31,60,943/- 2009 -2012
Study of hepatitis B virus (HBV) resistance patterns in patient with chronic infection during therapy with nucleoside and nucleotide analogues. Dr. Abhijit Chowdhury ICMR
Govt. of India
36,70,170/- 2009 -2011
Characterization of occult hepatitis B infection in Indian Patients with hepatocellular carcinoma (HCC) and in HCV/HIV carriers. Dr. Simanti Datta DST
Govt. of India
13,77,000/- 2009 -2012
Molecular Epidemiology of Hepatitis   B virus infection in Tripura. Dr. Simanti Datta ICMR, Govt. of India 38,84,963/- 2010 -2013
Assessment of Liver Diseases burden in the General population using ALT as a biomarker of Liver Disease and standardization of Normal ALT in our population Dr Abhijit Chowdhury DST, West Bengal 26,11,200/- 2011-2014
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